DEVELOPMENT OF NANOMATERIAL BASED MICROFLUIDIC POINT OF CARE TESTING DEVICE

Manasi Mahajan, Manisha R., Reena Monica P.

Abstract: Microfluidics has emerged as a transformative field that manipulates small amounts of fluids to revolutionize diagnostics. Integrating microfluidic devices into point-of-care testing improves accuracy, speed and accessibility, ultimately improving patient care. These devices enable fast and accurate analysis through efficient mass transport mechanisms. Microfluidic devices typically consist of micro channels, micropumps and microreactors. Some common applications include point-of-care diagnostics, DNA analysis, drug delivery, chemical synthesis, and environmental monitoring. Organ-on-chip (OOC) technology comprises living cells arranged to mimic the mechanical and physiological characteristics of actual organs. Typically, OOC devices are built of small channels or chambers connected by microfluidics that are transparent, like silicone or glass. The complex web of blood arteries and tissues seen in actual organs is replicated in these channels. Applications for OOC (Organ-On-A-Chip) technology are numerous and span a number of industries, including toxicology, pharmaceutical development, biomedical research, and personalized medicine. The design of Organ on chip design is designed, modelled and analysed in Ansys Fluent software.

Keywords: Microfluidics, Point of care devices, Organ on Chip, Polydimethylsiloxane, Extracellular Matrix, Sensitivity, Ansys Fluent, Microchannel, Versatility

DOI: 10.24874/PES08.02B.012

Recieved: 19.04.2025  Revised: 12.06.2025  Accepted: 17.07.2025  
UDC:

Reads: 3   

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